Importantly, reported use of the drug declined temporarily during periods of social distancing during the early phases of the COVID-19 pandemic, coinciding with the closure of nightlife and the cancellation of events where MDMA is typically consumed. Of the 13 EU countries that undertook surveys since 2021 and provided confidence intervals, four reported higher estimates than their previous comparable survey, nine reported stable estimates and one reported a decrease. General population surveys in many countries showed that MDMA prevalence was declining from peak levels attained in the early to mid-2000s. Data on prevalence of use provide an indication of the structure, location and approximate size of retail MDMA markets in the European Unio

When using wastewater data to estimate MDMA markets, the use of MDMA is based on the excreted parent drug, rather than on an excreted metabolite (which is the case for some other drugs, such as cocaine and heroin


The demand for stimulants in social environments appears to be resilient more broadly, even in the face of such market shocks. Options for future regulated online sales exist but need to account for problems such as the lack of face-to-face interaction with a vendor (and the potential loss of key tailored harm reduction which can be given in person), and meaningful enforcement of age controls. The pull factors of the darknet in the current illegal market highlight important challenges for a regulated market. This is up from 48.7% in 2015, when the percentage was also higher than for any other dru


More rarely, almost pure MDMA base in liquid form has been buy ecstasy sold to consumers, which represents a serious health risk (Drugs Information Monitoring System [DIMS], 2022). Additional data were shared with the EUDA by the Drug information and Monitoring System (DIMS) in the Netherlands. However, these data are not generalisable either, and as such should be interpreted with caution. Samples submitted to drug-checking services can also provide an indication of the products available to consumers. These products typically contain MDMA hydrochloride (see Box Forms of MDMA present on the European market

As so often, enforcement interventions have failed to prevent rising use, or prevent supply in the longer term, instead only serving to temporarily displace using behaviours and mutate the market in ways that increased health harm

These metabolites are chemicals produced as the body processes MDMA, which linger in the system, offering a window into recent drug use. For MDMA, this involves identifying traces of the drug’s metabolites. Drug tests aim to detect the presence of specific substances in the body. It typically appears on drug tests as MDMA or buy ecstasy sometimes under its street names, Ecstasy or Molly.
Ecstasy adulteration is responsive to market pressures


According to 2021 data, tablets and powders/crystals share the EU MDMA market equally, with some variability among countries in terms of preference for either ecstasy tablets or MDMA powders/crystals buy ecstasy (see Figure 6.1. Distribution of usual MDMA forms across countries). Analysis of drugs sold as MDMA/ecstasy in Australia shows that these contain a wide range of substances, and some contain no MDMA at all. Vendors in the Netherlands appear to be developing a fairly successful international trade of ecstasy-type drugs and stimulants from cryptomarkets, but it appears that most countries are selling illicit drugs within domestic borders. Three quarters of all Dutch revenues from illicit drugs sold on cryptomarkets were from two drug categories — ecstasy-type drugs and stimulants. In the Netherlands, in 2022, the price of 1 kilogram of (locally produced) MDMA crystals was reported at EUR 2 300, whereas 1 litre of MDMA oil (which can be converted into crystals or powder, and subsequently ecstasy tablets) was reported at EUR per litr

While individual tablet weight cannot be a direct predictor of how much MDMA is present in each tablet, at population level this trend is consistent when comparing larger ecstasy tablets (almost always containing more MDMA) with smaller tablets (almost always containing less MDMA). This means that consumers buying ecstasy tablets in Europe in 2019 would obtain a product containing up to almost double the highest amount of MDMA recorded in ecstasy tablets in 2011. In Australia, in January 2024, potent opioids of the nitazene family were found in brightly coloured tablets with logos reminiscent of ecstasy tablets. In tablets, adulterants typically include stimulants and MDMA-type substances – other phenethylamines with comparable subjective effects, such as MDA (3). Caffeine is the adulterant most commonly found in ecstasy tablets as well as in MDMA powders and crystals. Adulteration appears to be more frequent in ecstasy tablets than in MDMA crystals.
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While the population of Brussels is larger than that of Stockholm, the amount of MDMA consumed is almost 30 % higher in Stockholm. Estimates based on wastewater data for MDMA were noted to be more than double the amount estimated by the demand-based estimate. In a study commissioned for this analysis, wastewater estimates were found to give different results, either higher or lower, than demand-based estimates, depending on the drug concerned. In these cases, the missing information was replaced with the mean, computed on the remaining countries. In calculating the amounts used, it was assumed that the maximum realistic amount to use in a day was five tablets; those reporting higher values were excluded.
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